Adrafinil is a nootropic that is used to promote alertness and prevent feelings of sleepiness. Adrafinil is also used as means of increasing focus, supporting memory, and improving overall learning capacity.
Adrafinil is sometimes used as a prescription drug for people suffering from narcolepsy as a means of keeping them awake longer.
In the body, adrafinil has a relatively short half-life but is converted into modafinil, which has a much longer half-life and thus longer-lasting effects. For those who are subjected to drug testing, adrafinil is prohibited for in-competition use by the World Anti-Doping Agency (WADA).
It’s a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention in elderly patients. It is also used off-label by individuals wishing to avoid fatigue, such as night workers or others who need to stay awake and alert for long periods of time. Adrafinil does not currently have FDA approval and is thus unregulated in the United States. It was marketed in France and elsewhere in Europe under the trade name Olmifon until September 2011 when France’s FDA equivalent reassessed the drug and withdrew marketing permission
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It’s a prodrug; it is primarily metabolized in vivo to modafinil, resulting in nearly identical pharmacological effects. Unlike modafinil, however, it takes time for the metabolite to accumulate to active levels in the bloodstream. Effects usually are apparent within 45–60 minutes when taken orally on an empty stomach.
The recommended dosage for adrafinil is approximately 10mg/kg. This works out to approximately 600-900mg in most people. It is important to take adrafinil early in the morning if you wish to continue a regular sleep cycle. The effects generally last somewhere between 12-15 hours.
Should not be taken daily and should not be taken for long periods of time. Instead, the most common dosage schedule is to use modafinil only when needed and to avoid use on consecutive days. In those who are subject to WADA drug testing, keep in mind that adrafinil is a banned in-competition substance